cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

Base Information

Chemical Name:cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine
CAS No.:1352419-56-7
Molecular Formula:C₁₂H₁₃F₄N₃O
Molecular Weight:291.248
Hs Code.:

Synonyms:cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

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Technology Process of cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

There total 1 articles about cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1352419-56-7
cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

Guidance literature:

Reference yield: 20.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1352419-56-7
cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

: 1352420-58-6
C₁₇H₂₁F₄N₃O₃

Guidance literature:: In dichloromethane; at 20 ℃; for 20h;

Reference yield:

: 1352419-56-7
cis/trans-rac-5-(5-amino-2-fluorophenyl)-5-methyl-6-trifluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-ylamine

: 1352416-75-1
N-{3-[(2R,3R)-5-amino-3-methyl-2-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl}-5-methoxypyrazine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 20 h / 20 °C

2: 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride / methanol / 20 h / 0 °C

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In methanol; dichloromethane;