N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine

Base Information

• Chemical Name: N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine
• CAS No.: 342793-41-3
• Molecular Formula: C₁₉H₂₂INO₃S
• Molecular Weight: 471.359
• Mol file: 342793-41-3.mol

Synonyms:N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine

Chemical Property of N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine

There total 1 articles about N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

4-Methoxystyrene (637-69-4,24936-44-5) + 4-methyl-N-(2-propenyl)benzenesulfonamide (50487-71-3) → N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine (342793-41-3)

Guidance literature:

With N-iodo-succinimide; In dichloromethane; at -78 - 0 ℃;

DOI:10.1016/S0040-4020(02)01448-5

Reference yield: 87.0%

N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine (342793-41-3) → 4-methyl-1-[(4-methylphenyl)sulfonyl]-2-(4-methoxyphenyl)pyrrolidine

Guidance literature:

With N-ethylpiperidine hypophosphite; cetyltrimethylammonim bromide; 2,2’-azobis[2-(2-imidazolin-2-yl)propane]dihydrochloride; In water; at 80 ℃; for 6h;

DOI:10.1016/S0040-4020(02)01448-5

Reference yield:

N-[2-iodo-1-(4-methoxyphenyl)ethyl]-N-[(4-methylphenyl)sulfonyl]prop-2-enylamine (342793-41-3) → cis-4-methyl-1-[(4-methylphenyl)sulfonyl]-2-(4-methoxyphenyl)pyrrolidine + trans-4-methyl-1-[(4-methylphenyl)sulfonyl]-2-(4-methoxyphenyl)pyrrolidine

Guidance literature:

With N-ethylpiperidine hypophosphite; cetyltrimethylammonim bromide; 2,2’-azobis[2-(2-imidazolin-2-yl)propane]dihydrochloride; In water; at 80 ℃; for 6h; Title compound not separated from byproducts.;

DOI:10.1021/ol010014p

upstream raw materials:

4-Methoxystyrene

4-methyl-N-(2-propenyl)benzenesulfonamide