4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Base Information

Chemical Name:4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine
CAS No.:851346-08-2
Molecular Formula:C₄₁H₅₅N₃O₆Si₂
Molecular Weight:742.075
Hs Code.:

Synonyms:4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Suppliers and Price of 4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

There total 4 articles about 4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 851346-07-1
4-amino-1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidin-2-one

: 93-97-0
benzoic acid anhydride

: 851346-08-2
4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Guidance literature:: With pyridine; dmap; at 20 ℃; for 8h;
DOI:10.1002/chem.200401114

Reference yield:

: 851345-90-9
3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethylenethymidine

: 851346-08-2
4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Guidance literature:: Multi-step reaction with 3 steps

1: DMAP; Et₃N / acetonitrile / 1.5 h / 0 °C

2: 71 mg / NH₄OH / acetonitrile / 3 h / 0 - 20 °C

3: 88 percent / DMAP; pyridine / 8 h / 20 °C

With pyridine; dmap; ammonium hydroxide; triethylamine; In acetonitrile;
DOI:10.1002/chem.200401114

Reference yield:

: 2,4,6-triisopropyl-benzenesulfonic acid 1-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxymethyl-tetrahydro-furan-2-yl]-5-methyl-2-oxo-1,2-dihydro-pyrimidin-4-yl ester

: 851346-08-2
4-N-benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-C-methoxymethyl-5-methylcytidine

Guidance literature:: Multi-step reaction with 2 steps

1: 71 mg / NH₄OH / acetonitrile / 3 h / 0 - 20 °C

2: 88 percent / DMAP; pyridine / 8 h / 20 °C

With pyridine; dmap; ammonium hydroxide; In acetonitrile;
DOI:10.1002/chem.200401114