(2-(O-Tolyl)thiazol-4-YL)methanamine

Base Information

Chemical Name:(2-(O-Tolyl)thiazol-4-YL)methanamine
CAS No.:885280-68-2
Molecular Formula:C₁₁H₁₂N₂S
Molecular Weight:204.296
Hs Code.:
DSSTox Substance ID:DTXSID70586189
Wikidata:Q82478266
Mol file:885280-68-2.mol

Synonyms:885280-68-2;C-(2-O-TOLYL-THIAZOL-4-YL)-METHYLAMINE;(2-(O-TOLYL)THIAZOL-4-YL)METHANAMINE;1-[2-(2-Methylphenyl)-1,3-thiazol-4-yl]methanamine;2-(2-METHYLPHENYL)-4-THIAZOLEMETHANAMINE;MFCD06738419;[2-(2-METHYLPHENYL)-1,3-THIAZOL-4-YL]METHANAMINE;(2-o-Tolyl-thiazol-4-yl)methylamine;DTXSID70586189;AKOS000320849;AB27131;MCULE-4705710250;DB-077849;CS-0357117;A861873

Suppliers and Price of (2-(O-Tolyl)thiazol-4-YL)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
C-(2-O-Tolyl-thiazol-4-yl)-methylamine
50mg
$ 90.00

Crysdot
(2-(o-Tolyl)thiazol-4-yl)methanamine 97%
5g
$ 1229.00

Chemenu
C-(2-o-Tolyl-thiazol-4-yl)-methylamine 97%
5g
$ 1149.00

American Custom Chemicals Corporation
C-(2-O-TOLYL-THIAZOL-4-YL)-METHYLAMINE 96.00%
5MG
$ 495.09

Alichem
(2-(o-Tolyl)thiazol-4-yl)methanamine
1g
$ 295.36

AK Scientific
C-(2-o-Tolyl-thiazol-4-yl)-methylamine
1g
$ 306.00

Total 8 raw suppliers

Chemical Property of (2-(O-Tolyl)thiazol-4-YL)methanamine

Chemical Property:

Boiling Point:368.6±44.0 °C(Predicted)
PKA:7.47±0.29(Predicted)
PSA：67.15000
Density:1.176±0.06 g/cm3(Predicted)
LogP:3.27750
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:204.07211956
Heavy Atom Count:14
Complexity:186

Purity/Quality:

97% ^*data from raw suppliers

C-(2-O-Tolyl-thiazol-4-yl)-methylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=NC(=CS2)CN

Technology Process of (2-(O-Tolyl)thiazol-4-YL)methanamine

There total 3 articles about (2-(O-Tolyl)thiazol-4-YL)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 91349-33-6
4-chloromethyl-2-o-tolyl-thiazole

: 885280-68-2
C₁₁H₁₂N₂S

Guidance literature:: 4-chloromethyl-2-o-tolyl-thiazole; With potassium phtalimide; In N,N-dimethyl-formamide; at 80 ℃;

With hydrazine hydrate; In ethanol; at 20 ℃;
DOI:10.1016/j.bmc.2019.05.029

Reference yield:

: 527-85-5
o-Methylbenzamid

: 885280-68-2
C₁₁H₁₂N₂S

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetraphosphorus decasulfide / diethyl ether / Heating

2.1: 130 °C

3.1: potassium phtalimide / N,N-dimethyl-formamide / 80 °C

3.2: 20 °C

With tetraphosphorus decasulfide; potassium phtalimide; In diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2019.05.029

Reference yield:

: 53515-19-8
2-methylthiobenzamide

: 885280-68-2
C₁₁H₁₂N₂S

Guidance literature:: Multi-step reaction with 2 steps

1.1: 130 °C

2.1: potassium phtalimide / N,N-dimethyl-formamide / 80 °C

2.2: 20 °C

With potassium phtalimide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2019.05.029