N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

Base Information

Chemical Name:N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide
CAS No.:161314-70-1
Molecular Formula:C₁₈H₂₃N₃O₅S
Molecular Weight:393.464
Hs Code.:

Synonyms:N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

Chemical Property:

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Technology Process of N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

There total 12 articles about N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 477908-17-1
methyl 2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanoate

: 161314-70-1
N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

Guidance literature:: With hydroxylamine hydrochloride; sodium methylate; In methanol; at 20 ℃; for 48h;
DOI:10.1002/jlcr.570

Reference yield:

: 3099-31-8
nicotinyl chloride

: 161314-70-1
N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](3-picolyl)amino]-3-methylbutanamide

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide

2: MaOMe; HONH₂*HCl / methanol / 20 °C

With hydroxylamine hydrochloride; potassium carbonate; In methanol; N,N-dimethyl-formamide;