ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

Base Information

Chemical Name:ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate
CAS No.:1350469-22-5
Molecular Formula:C₃₉H₃₆F₃N₃O₇
Molecular Weight:715.726
Hs Code.:

ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

Synonyms:ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

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Chemical Property of ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

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Technology Process of ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

There total 22 articles about ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1350468-50-6
ethyl (R)-1-(hydroxymethyl)-2-methyl-3-oxoisoindoline-1-carboxylate

: 1350469-51-0
2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)acetic acid

: 1350469-22-5
ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 2-methyltetrahydrofuran; at 20 ℃; for 5h;

Reference yield: 100.0%

: 1350469-24-7
ethyl (1R)-1-({2-[4-amino-3-(dimethylcarbamoyl)phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

: 256397-64-5
[6-METHYL-4'-(TRIFLUOROMETHYL)-[1, 1'-BIPHENYL]-2-CARBONYL]

: 1350469-22-5
ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 256397-61-2
6-methyl-4'-trifluoromethyl-1,1'-biphenyl-2-carboxylic acid

: 1350469-22-5
ethyl-(R)-1-((2-(3-(dimethylcarbamoyl)-4-(6-methyl-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-carboxamido)phenyl)-acetoxy)methyl)-2-methylisoindoline-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In dichloromethane;