(S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate

Base Information

• Chemical Name: (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate
• CAS No.: 1403755-49-6
• Molecular Formula: C₂₅H₃₄FN*ClHO₄
• Molecular Weight: 468.009
• Mol file: 1403755-49-6.mol

Synonyms:(S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate

Chemical Property of (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate

There total 3 articles about (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(S)-2-{bis[4-(tert-butyl)phenyl]fluoromethyl}pyrrolidine (1403755-27-0) → (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate (1403755-49-6)

Guidance literature:

With perchloric acid; In diethyl ether; water;

DOI:10.1002/chem.201201316

Reference yield:

(S)-α,α-Bis(4-(1,1-dimethylethyl)phenyl)-2-pyrrolidinemethanol (131180-55-7) → (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate (1403755-49-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diethylamino-sulfur trifluoride / dichloromethane / 8 h / 0 °C

2: perchloric acid / diethyl ether; water

With perchloric acid; diethylamino-sulfur trifluoride; In diethyl ether; dichloromethane; water;

DOI:10.1002/chem.201201316

Reference yield:

(S)-(1-benzylpyrrolidin-2-yl)bis[4-(tert-butyl)phenyl]methanol (1403755-28-1) → (S)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)pyrrolidinium perchlorate (1403755-49-6)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; palladium 10% on activated carbon; hydrogen / ethanol / 48 h / 20 °C

2: diethylamino-sulfur trifluoride / dichloromethane / 8 h / 0 °C

3: perchloric acid / diethyl ether; water

With perchloric acid; diethylamino-sulfur trifluoride; sulfuric acid; palladium 10% on activated carbon; hydrogen; In diethyl ether; ethanol; dichloromethane; water;

DOI:10.1002/chem.201201316

upstream raw materials:

(S)-(1-benzylpyrrolidin-2-yl)bis[4-(tert-butyl)phenyl]methanol

(S)-α,α-Bis(4-(1,1-dimethylethyl)phenyl)-2-pyrrolidinemethanol

(S)-2-{bis[4-(tert-butyl)phenyl]fluoromethyl}pyrrolidine

Downstream raw materials:

(S,E)-2-(bis(4-(tert-butyl)phenyl)fluoromethyl)-1-((E)-3-phenylallylidene)pyrrolidinium perchlorate

(E)-1-(3-phenylallylidene)pyrrolidinium perchlorate