Technology Process of C13H13N
There total 3 articles about C13H13N which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; potassium carbonate;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/ol3017353
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine / toluene / 20 °C / Inert atmosphere
2: water; potassium carbonate / tetrahydrofuran; methanol / 2 h / 20 °C / Inert atmosphere
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); water; potassium carbonate; diisopropylamine;
In
tetrahydrofuran; methanol; toluene;
1: Sonogashira coupling;
DOI:10.1021/ol3017353
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethylenediamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere
1.2: 9 h / 150 °C / Inert atmosphere
2.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); diisopropylamine / toluene / 20 °C / Inert atmosphere
3.1: water; potassium carbonate / tetrahydrofuran; methanol / 2 h / 20 °C / Inert atmosphere
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); water; potassium carbonate; ethylenediamine; diisopropylamine;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene;
2.1: Sonogashira coupling;
DOI:10.1021/ol3017353
