2-methoxy-3-methylbenzonitrile

Base Information

• Chemical Name: 2-methoxy-3-methylbenzonitrile
• CAS No.: 53078-68-5
• Molecular Formula: C₉H₉NO
• Molecular Weight: 147.177
• Hs Code.: 2926907090

Synonyms:2-methoxy-3-methylbenzonitrile

Chemical Property of 2-methoxy-3-methylbenzonitrile

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxy-3-methylbenzonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-3-methylbenzonitrile

There total 4 articles about 2-methoxy-3-methylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-methoxy-1,3-dimethylbenzene (1004-66-6) → 2-methoxy-3-methylbenzonitrile (53078-68-5)

Guidance literature:

With tert.-butylnitrite; N-hydroxyphthalimide; palladium diacetate; In acetonitrile; at 70 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201305731

Reference yield:

2-methylmethoxybenzene (578-58-5) + (3,5-bis(trifluoromethyl)phenyl)(cyano)-l3-iodanyl trifluoromethanesulfonate → 2-methoxy-3-methylbenzonitrile (53078-68-5) + 4-methoxy-3-methylbenzonitrile (53078-71-0)

Guidance literature:

With iron(II) acetate; In 1,2-dichloro-ethane; at 70 ℃; for 24h; Overall yield = 76 %; Overall yield = 34 mg; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201309791

Reference yield:

2-methoxy-3-methyl-benzoic acid amide (90609-90-8) → 2-methoxy-3-methylbenzonitrile (53078-68-5)

Guidance literature:

With phosphorus pentachloride;

upstream raw materials:

2-methoxy-3-methyl-benzoic acid amide

2-methoxy-3-methylbenzoyl chloride

2-methoxy-1,3-dimethylbenzene

2-methylmethoxybenzene

Downstream raw materials:

2-methoxy-3-methyl-benzophenone-imine

2-methoxy-3-methyl-benzophenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 53078-68-5 2-methoxy-3-methylbenzonitrile

Send

Send

Metric Ton KG G Pound L ML

Send

Send