tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Base Information

Chemical Name:tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate
CAS No.:1312771-10-0
Molecular Formula:C₄₁H₅₂ClN₅O₁₁
Molecular Weight:826.344
Hs Code.:

tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Synonyms:tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Suppliers and Price of tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

There total 3 articles about tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1312771-08-6
tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-7-oxo-3-thioxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

: 3332-29-4
O-ethylhydroxylamine hydrochloride

: 1312771-10-0
tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Guidance literature:: With mercury(II) diacetate; triethylamine; In tetrahydrofuran; methanol; for 1.5h; Cooling with ice;

Reference yield:

: 1312770-12-9
tert-butyl 4-[(1R)-1-isocyanatobutyl]-2-nitrobenzoate

: 1312771-10-0
tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium tert-butylate / acetonitrile; tetrahydrofuran / 0.5 h / Cooling with ice

2: Lawessons reagent / tetrahydrofuran / 16 h / Cooling with ice

3: triethylamine; mercury(II) diacetate / tetrahydrofuran; methanol / 1.5 h / Cooling with ice

With Lawessons reagent; potassium tert-butylate; mercury(II) diacetate; triethylamine; In tetrahydrofuran; methanol; acetonitrile;

Reference yield:

: 1312771-09-7
tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

: 1312771-10-0
tert-butyl 4-[(1R)-1-({[(6R)-6-(5-chloro-2-methoxybenzyl)-3-(ethoxyimino)-7-oxo-4-(2,4,6-trimethoxybenzyl)-1,4-diazepan-1-yl]carbonyl}amino)butyl]-2-nitrobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: Lawessons reagent / tetrahydrofuran / 16 h / Cooling with ice

2: triethylamine; mercury(II) diacetate / tetrahydrofuran; methanol / 1.5 h / Cooling with ice

With Lawessons reagent; mercury(II) diacetate; triethylamine; In tetrahydrofuran; methanol;