N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Base Information

Chemical Name:N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine
CAS No.:1268600-48-1
Molecular Formula:C₄₁H₅₉NO₆Si₂
Molecular Weight:718.094
Hs Code.:

N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Synonyms:N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Suppliers and Price of N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

There total 4 articles about N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1268600-42-5
3-(methylbenzyloxy)cyclobut-1-enone

: 1268600-47-0
(3R,4S)-N-(2-trimethylsilylethoxycarbonyl)-N-(2-propenyl)-hex-5-en-3-benzyloxymethyl-4-(tert-butyldimethylsilanyloxy)-1-ynylamine

: 1268600-48-1
N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Guidance literature:: In toluene; at 80 ℃; for 3h; Inert atmosphere; Reflux;
DOI:10.1021/jo2000308

Reference yield:

: 279257-13-5
2-(trimethylsilyl)ethyl allylcarbamate

: 1268600-48-1
N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium phosphate; copper(ll) sulfate pentahydrate; 1,10-Phenanthroline / toluene / 48 h / 85 - 90 °C / Inert atmosphere

2: toluene / 3 h / 80 °C / Inert atmosphere; Reflux

With potassium phosphate; 1,10-Phenanthroline; copper(ll) sulfate pentahydrate; In toluene;
DOI:10.1021/jo2000308

Reference yield:

: 66222-28-4
(benzyloxymethyl)tributylstannane

: 1268600-48-1
N-allyl-N-(2-trimethylsilanyloxycarbonyl)-2-(1R,2S)-[1-(benzyloxy)methyl-2-(tert-butyldimethylsilanyloxy)but-3-enyl]-3-hydroxy-5-(benzyloxy)methylphenylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -78 °C / Inert atmosphere

1.2: 2.5 h / -78 °C / Inert atmosphere

1.3: 3 h / -78 °C / Inert atmosphere

2.1: toluene / 3 h / 80 °C / Inert atmosphere; Reflux

With n-butyllithium; In tetrahydrofuran; hexane; toluene;
DOI:10.1021/jo2000308