methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate

Base Information

• Chemical Name: methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate
• CAS No.: 208399-53-5
• Molecular Formula: C₃₉H₃₂O₉
• Molecular Weight: 644.678

Synonyms:methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate

Chemical Property of methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate

There total 10 articles about methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]benzaldehyde (208399-40-0) + [4-Benzoyloxy-3-(4-methoxycarbonyl-phenoxy)-benzyl]-triphenyl-phosphonium; bromide → methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate (208399-53-5)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In dichloromethane; for 24h; Heating;

DOI:10.1002/(SICI)1099-0690(199805)1998:5<877::AID-EJOC877>3.0.CO;2-S

Reference yield:

methyl 3-nitro-4-chlorobenzoate (14719-83-6) → methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate (208399-53-5)

Guidance literature:

Multi-step reaction with 8 steps

1: 1.) NaH / 1.) DMF, 20 deg C, 10 min; 2.) DMF, 20 deg C, 2 h

2: 85 percent / 5percent Pd/C, H₂ / ethyl acetate / 6 h / 3750.3 Torr

3: 84 percent / NaNO₂, 50percent H₃PO₂ / H₂O / 2 h, 0 deg C, 5 h, 20 deg C

4: 81 percent / AlCl₃ / benzene / 15 h / Heating

5: 81 percent / Na₂CO₃ / ethanol; H₂O / 5 h / 20 °C

6: NBS, AIBN / CCl₄ / 2 h / Heating

7: toluene / 15 h / 100 °C

8: 89 percent / K₂CO₃, 18-crown-6 / CH₂Cl₂ / 24 h / Heating

With palladium on activated charcoal; N-Bromosuccinimide; aluminium trichloride; 18-crown-6 ether; 2,2'-azobis(isobutyronitrile); hydrogen; hypophosphorous acid; sodium hydride; sodium carbonate; potassium carbonate; sodium nitrite; In tetrachloromethane; ethanol; dichloromethane; water; ethyl acetate; toluene; benzene;

DOI:10.1002/(SICI)1099-0690(199805)1998:5<877::AID-EJOC877>3.0.CO;2-S

Reference yield:

5-methyl-2-methoxyphenol (1195-09-1) → methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate (208399-53-5)

Guidance literature:

Multi-step reaction with 8 steps

1: 1.) NaH / 1.) DMF, 20 deg C, 10 min; 2.) DMF, 20 deg C, 2 h

2: 85 percent / 5percent Pd/C, H₂ / ethyl acetate / 6 h / 3750.3 Torr

3: 84 percent / NaNO₂, 50percent H₃PO₂ / H₂O / 2 h, 0 deg C, 5 h, 20 deg C

4: 81 percent / AlCl₃ / benzene / 15 h / Heating

5: 81 percent / Na₂CO₃ / ethanol; H₂O / 5 h / 20 °C

6: NBS, AIBN / CCl₄ / 2 h / Heating

7: toluene / 15 h / 100 °C

8: 89 percent / K₂CO₃, 18-crown-6 / CH₂Cl₂ / 24 h / Heating

With palladium on activated charcoal; N-Bromosuccinimide; aluminium trichloride; 18-crown-6 ether; 2,2'-azobis(isobutyronitrile); hydrogen; hypophosphorous acid; sodium hydride; sodium carbonate; potassium carbonate; sodium nitrite; In tetrachloromethane; ethanol; dichloromethane; water; ethyl acetate; toluene; benzene;

DOI:10.1002/(SICI)1099-0690(199805)1998:5<877::AID-EJOC877>3.0.CO;2-S

upstream raw materials:

3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]benzaldehyde

methyl 3-nitro-4-chlorobenzoate

5-methyl-2-methoxyphenol

meta-hydroxybenzaldehyde

Downstream raw materials:

methyl 4-(2-benzoyloxy-5-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenethyl}phenoxy)benzoate

benzyl ether of (E)-dehydromarchantin I

4-{2-[3-(2-[1,3]Dioxolan-2-yl-4-methoxy-phenoxy)-phenyl]-ethyl}-2-(4-hydroxymethyl-phenoxy)-phenol

[4-(2-benzyloxy-5-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenethyl}phenoxy)phenyl]methanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 208399-53-5 methyl 4-[2-benzoyloxy-5-((E/Z)-2-{3-[2-(1,3-dioxolan-2-yl)-4-methoxyphenoxy]phenyl}-1-ethenyl)phenoxy]benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send