N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

Base Information

Chemical Name:N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide
CAS No.:359822-95-0
Molecular Formula:C₁₆H₁₄N₄O₂
Molecular Weight:294.313
Hs Code.:

Synonyms:N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

Suppliers and Price of N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

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Technology Process of N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

There total 3 articles about N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 144835-67-6
2-methyl-4H-imidazo[1,2-a]pyridine-3-carbohydrazide

: 359822-95-0
N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

Guidance literature:: With sulfuric acid; In ethanol; Reflux;
DOI:10.1016/j.bmc.2014.05.038

Reference yield:

: 2549-19-1
ethyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate

: 359822-95-0
N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol; water / 3 h / Reflux

2: sulfuric acid / ethanol / Reflux

With sulfuric acid; hydrazine hydrate; In ethanol; water;
DOI:10.1016/j.bmc.2014.05.038

Reference yield:

: 504-29-0
2-aminopyridine

: 359822-95-0
N'-(4-hydroxybenzylidene)-2-methylimidazo[1,2-a]pyridine-3-carbohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,2-dimethoxyethane / 6 h / 90 °C

2: hydrazine hydrate / ethanol; water / 3 h / Reflux

3: sulfuric acid / ethanol / Reflux

With sulfuric acid; hydrazine hydrate; In 1,2-dimethoxyethane; ethanol; water;
DOI:10.1016/j.bmc.2014.05.038