(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Base Information

Chemical Name:(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine
CAS No.:681171-39-1
Molecular Formula:C₂₄H₃₁N₃O₂
Molecular Weight:393.529
Hs Code.:

Synonyms:(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Suppliers and Price of (3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

There total 4 articles about (3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 681171-38-0
(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-allyl)-dimethylamine

: 681171-39-1
(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 2585.74 Torr;
DOI:10.1016/j.bmcl.2004.06.043

Reference yield:

: 31558-41-5
4-bromo-2,5-dimethoxybenzaldehyde

: 681171-39-1
(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Guidance literature:: Multi-step reaction with 6 steps

1.1: 100 percent / TsOH / benzene

2.1: BuLi / tetrahydrofuran / -78 °C

2.2: 85 percent / B(OEt)3 / tetrahydrofuran

3.1: Pd(PPh₃)4; aq. Na₂CO₃ / ethanol / 90 °C

4.1: 95 percent / aq. AcOH / tetrahydrofuran

5.1: LiN(Si(CH₃)3)2

6.1: 28 percent / H₂ / Pd/C / ethanol / 2585.74 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; hydrogen; sodium carbonate; toluene-4-sulfonic acid; acetic acid; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; ethanol; benzene; 3.1: Suzuki coupling / 5.1: Wittig condensation;
DOI:10.1016/j.bmcl.2004.06.043

Reference yield:

: 681171-33-5
2-(4-boronic acid-2,5-dimethoxy-phenyl)-[1,3]dioxolane

: 681171-39-1
(3-{4-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-2-yl]-2,5-dimethoxy-phenyl}-propyl)-dimethylamine

Guidance literature:: Multi-step reaction with 4 steps

1: Pd(PPh₃)4; aq. Na₂CO₃ / ethanol / 90 °C

2: 95 percent / aq. AcOH / tetrahydrofuran

3: LiN(Si(CH₃)3)2

4: 28 percent / H₂ / Pd/C / ethanol / 2585.74 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; sodium carbonate; acetic acid; lithium hexamethyldisilazane; palladium on activated charcoal; In tetrahydrofuran; ethanol; 1: Suzuki coupling / 3: Wittig condensation;
DOI:10.1016/j.bmcl.2004.06.043