(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Base Information

Chemical Name:(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt
CAS No.:1059630-13-5
Molecular Formula:C₈H₈O₃*C₁₁H₁₃BrN₂
Molecular Weight:405.291
Hs Code.:

Synonyms:(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Suppliers and Price of (4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2-Hydroxy-2-phenylaceticAcid
50mg
$ 45.00

Crysdot
(4aS,9bR)-6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole(S)-2-hydroxy-2-phenylacetate 97%
5g
$ 640.00

Chemenu
(4aS,9bR)-6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole(S)-2-hydroxy-2-phenylacetate 95+%
5g
$ 604.00

ACHEMBLOCK
(2S)-2-hydroxy-2-phenylaceticacid;(4aS,9bR)-6-bromo-1H,2H,3H,4H,4aH,5H,9bH-pyrido[4,3-b]indole 97%
5G
$ 395.00

ACHEMBLOCK
(2S)-2-hydroxy-2-phenylaceticacid;(4aS,9bR)-6-bromo-1H,2H,3H,4H,4aH,5H,9bH-pyrido[4,3-b]indole 97%
1G
$ 135.00

Total 27 raw suppliers

Chemical Property of (4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

(2S)-2-Hydroxy-2-phenylaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

There total 4 articles about (4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

: 439928-25-3
6-bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

: 17199-29-0
(S)-Mandelic acid

: 1059630-13-5
(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Guidance literature:: 6-bromo-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole; With isopropyl alcohol; sodium hydroxide; In aq. phosphate buffer; water; at 33 ℃; pH=6.7-6.9; Inert atmosphere; Enzymatic reaction;

(S)-Mandelic acid; at 50 - 55 ℃;

Reference yield: 41.0%

: 1059630-07-7
[4aS,9bR]-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

: 17199-29-0
(S)-Mandelic acid

: 1059630-13-5
(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Guidance literature:: In ethanol; at 20 - 50 ℃; for 2h;

Reference yield: 33.0%

: 1059630-12-4
racemate 6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole

: 17199-29-0
(S)-Mandelic acid

: 1059630-13-5
(4aS,9bR)-6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole (S)-(+)-mandelic acid salt

Guidance literature:: racemate 6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; With (R)-Mandelic Acid; In methanol; tert-butyl methyl ether; at 15 - 50 ℃; for 30 - 40h; Resolution of racemate;

With sodium hydroxide; In water; pH=~ 14;

(S)-Mandelic acid; In methanol; tert-butyl methyl ether; at 20 - 50 ℃; for 30 - 40h; Purification / work up;