tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester

Base Information

• Chemical Name: tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester
• CAS No.: 122174-73-6
• Molecular Formula: C₂₃H₂₉Cl₂NO₉S
• Molecular Weight: 566.457
• Mol file: 122174-73-6.mol

Synonyms:tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester

Chemical Property of tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester

There total 6 articles about tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aniline mustard (553-27-5) → tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester (122174-73-6)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine; NaBr; methanol

2: LiAlH₄

3: potassium ethylate; methanol / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin

With methanol; lithium aluminium tetrahydride; potassium ethoxide; bromine; sodium bromide;

Reference yield:

bis(4-aminophenyl)disulfide (722-27-0) → tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester (122174-73-6)

Guidance literature:

Multi-step reaction with 4 steps

2: POCl₃

3: LiAlH₄

4: potassium ethylate; methanol / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin

With methanol; lithium aluminium tetrahydride; potassium ethoxide; trichlorophosphate;

Reference yield:

N,N-bis-(2-chloro-ethyl)-4-thiocyanato-aniline (6952-14-3) → tri-O-acetyl-S-{4-[bis-(2-chloro-ethyl)-amino]-phenyl}-1-thio-β-D-glucopyranuronic acid methyl ester (122174-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄

2: potassium ethylate; methanol / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin

With methanol; lithium aluminium tetrahydride; potassium ethoxide;

upstream raw materials:

4-[bis-(2-chloro-ethyl)-amino]-thiophenol

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

bis(4-aminophenyl)disulfide

N,N-bis-(2-chloro-ethyl)-4-thiocyanato-aniline