4-O-benzyl-myo-inositol 1,3,5-orthoformate

Base Information

• Chemical Name: 4-O-benzyl-myo-inositol 1,3,5-orthoformate
• CAS No.: 120268-33-9
• Molecular Formula: C₁₄H₁₆O₆
• Molecular Weight: 280.277
• Mol file: 120268-33-9.mol

Synonyms:4-O-benzyl-myo-inositol 1,3,5-orthoformate

Chemical Property of 4-O-benzyl-myo-inositol 1,3,5-orthoformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-O-benzyl-myo-inositol 1,3,5-orthoformate

There total 8 articles about 4-O-benzyl-myo-inositol 1,3,5-orthoformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

racemic 4-O-benzyl-6-O-tosyl-myo-inositol 1,3,5-orthoformate → 4/6-O-benzyl-myo-inositol 1,3,5-monoorthoformate (120268-33-9,120330-00-9,122517-95-7,125356-34-5)

Guidance literature:

With magnesium; In methanol; at 60 ℃; for 24h;

DOI:10.1016/S0008-6215(02)00298-7

Reference yield: 88.0%

benzyl bromide (100-39-0) + myo-Inositol orthoformate (98510-20-4) → 4/6-O-benzyl-myo-inositol 1,3,5-monoorthoformate (120268-33-9,120330-00-9,122517-95-7,125356-34-5)

Guidance literature:

myo-Inositol orthoformate; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h;

benzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1039/b417757f

Reference yield: 72.0%

benzyl bromide (100-39-0) + myo-inositol-1,3,5-O-orthoformate → 4-O-benzyl-myo-inositol 1,3,5-orthoformate (120268-33-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 106 ℃; for 26h;

DOI:10.1016/j.tet.2004.11.025

upstream raw materials:

benzyl bromide

myo-Inositol orthoformate