8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

Base Information

Chemical Name:8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide
CAS No.:63177-04-8
Molecular Formula:C₂₂H₁₈ClFN₄O
Molecular Weight:408.863
Hs Code.:

8-chloro-6-(2-fluoro-phenyl)-1-methyl-4<i>H</i>-benzo[<i>f</i>]imidazo[1,5-<i>a</i>][1,4]diazepine-3-carboxylic acid cyclopropylamide

Synonyms:8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

Chemical Property:

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Technology Process of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

There total 3 articles about 8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59468-44-9
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid

: 765-30-0
Cyclopropylamine

: 63177-04-8
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

Guidance literature:: With phosphorus pentachloride; In ethanol; dichloromethane; water; ethyl acetate;

Reference yield:

: 59468-42-7
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid methyl ester

: 63177-04-8
8-chloro-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylic acid cyclopropylamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / methanol; water

2: phosphorus pentachloride / ethanol; dichloromethane; water; ethyl acetate

With potassium hydroxide; phosphorus pentachloride; In methanol; ethanol; dichloromethane; water; ethyl acetate;