C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE

Base Information

• Chemical Name: C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE
• CAS No.: 885272-87-7
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 204.228
• Hs Code.: 2934999090
• Mol file: 885272-87-7.mol

Synonyms:C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE

Chemical Property of C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE

Chemical Property:

• PSA: 61.28000
• LogP: 2.50920

Purity/Quality:

97% ^*data from raw suppliers

C-[2-(4-Methoxyphenyl)oxazol-4-yl]methylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE

There total 3 articles about C-[2-(4-METHOXY-PHENYL)-OXAZOL-4-YL]-METHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(chloromethyl)-2-(4-methoxyphenyl)oxazole (167155-56-8) + potassium phtalimide (1074-82-4) → C11H12N2O2 (885272-87-7)

Guidance literature:

4-(chloromethyl)-2-(4-methoxyphenyl)oxazole; potassium phtalimide; In N,N-dimethyl-formamide; at 80 ℃; for 5h;

With hydrazine hydrate; In ethanol; for 5h; Reflux;

DOI:10.1515/hc-2020-0117

Reference yield:

4-methoxyphenylacetamide (3424-93-9) → C11H12N2O2 (885272-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: neat (no solvent) / 4 h / 130 °C

2.1: N,N-dimethyl-formamide / 5 h / 80 °C

2.2: 5 h / Reflux

In N,N-dimethyl-formamide; 1.1: |Bredereck Imidazole Synthesis / 2.1: |Gabriel Amine Synthesis / 2.2: |Gabriel Amine Synthesis;

DOI:10.1515/hc-2020-0117

Reference yield:

C19H14N2O4 → C11H12N2O2 (885272-87-7)

Guidance literature:

With hydrazine hydrate; In ethanol; for 5h; Reflux;

DOI:10.1515/hc-2020-0117

upstream raw materials:

4-(chloromethyl)-2-(4-methoxyphenyl)oxazole

potassium phtalimide

4-methoxyphenylacetamide