167155-56-8

Basic information

• Product Name: 4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-1,3-OXAZOLE
• Synonyms: 4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-1,3-OXAZOLE
• CAS NO: 167155-56-8
• Molecular Formula: C₁₁H₁₀ClNO₂
• Molecular Weight: 223.6556
• Mol File: 167155-56-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-1,3-OXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-1,3-OXAZOLE(167155-56-8)
• EPA Substance Registry System: 4-(CHLOROMETHYL)-2-(4-METHOXYPHENYL)-1,3-OXAZOLE(167155-56-8)

Safety Data

• Hazardous Substances Data: 167155-56-8(Hazardous Substances Data)

Upstream product

• 154405-98-8 methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate 
• 885273-76-7 2-(4-methoxyphenyl)-4-hydroxymethyloxazole 
• 123-11-5 4-methoxy-benzaldehyde 
• 3424-93-9 4-methoxyphenylacetamide 
• 534-07-6 1,3-Dichloroacetone 

Downstream Products

• 885272-87-7 C₁₁H₁₂N₂O₂ 
• 851392-16-0 1-[2-(4-methoxy-phenyl)-oxazol-4-ylmethyl]-1H-[1,2,3]triazole 

Relevant articles and documents

Design, Synthesis and Biological Evaluation of N-((2-phenyloxazol-4-yl)methyl) Pyrimidine Carboxamide Derivatives as Potential Fungicidal Agents

Twelve N-((2-phenyloxazol-4-yl)methyl) pyrimidine carboxamide derivatives were designed, synthesized, and characterized by 1H NMR, 13C NMR, and HRMS. The fungicidal activities of these new compounds against Sclerotinia sclerotiorum, Botrytis cinereal, and Colletotrichum fragariae were evaluated. The results indicated that compounds 5b, 5f, and 5g displayed potential fungicidal activities against tested fungi, especially 5f exhibited IC50 value of 28.9 mg/L against S. sclerotiorum. Moreover, the compounds 5f and 5g showed IC50 values of 54.8 mg/L and 62.2 mg/L against C. fragariae respectively, which shows that they were more active than the commercial fungicide hymexazol. The superficial structure-activity relationships were discussed, which may be of benefit for the development of fungicides and discovery of novel fungicides.

COMPOUNDS AND METHODS for the inhibition of HDAC

Disclosed are compounds having the formula: wherein X1, X2, X3, R1, R2, R3, R4, Y, A, Z, L and n are as defined herein, and methods of making and using the same.

1-′(E)-2-(PHENYL) ETHENYL-4-(ARYLALKOXY)-OXAZOLE OR - THIAZOLE COMPOUNDS AS HER-2 TYROSINE KINASES INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER

Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms thereof, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their