C₁₅H₁₈F₃NO₂

Base Information

Chemical Name:C₁₅H₁₈F₃NO₂
CAS No.:1403595-59-4
Molecular Formula:C₁₅H₁₈F₃NO₂
Molecular Weight:301.309
Hs Code.:

C<sub>15</sub>H<sub>18</sub>F<sub>3</sub>NO<sub>2</sub>

Synonyms:C₁₅H₁₈F₃NO₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₅H₁₈F₃NO₂

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Technology Process of C₁₅H₁₈F₃NO₂

There total 3 articles about C₁₅H₁₈F₃NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1403597-85-2
methyl 3-(cyclopentyl(methyl)amino)-2-methyl-5-(trifluoromethyl)benzoate

: 1403595-59-4
C₁₅H₁₈F₃NO₂

Guidance literature:: methyl 3-(cyclopentyl(methyl)amino)-2-methyl-5-(trifluoromethyl)benzoate; With water; sodium hydroxide; In methanol; at 60 ℃; for 1h;

With hydrogenchloride; citric acid; In water; pH=4 - 6;

Reference yield:

: 13055-63-5
2-methyl-5-(trifluoromethyl)benzoic acid

: 1403595-59-4
C₁₅H₁₈F₃NO₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium carbonate / N,N-dimethyl-formamide / 4 h / 60 °C

2.1: hydrogen / palladium(II) hydroxide / methanol / 3 h

3.1: acetic acid / methanol / 3 h

4.1: caesium carbonate / acetonitrile / 8 h / 80 °C

5.1: sodium hydroxide; water / methanol / 1 h / 60 °C

5.2: pH 4 - 6

With water; hydrogen; sodium carbonate; caesium carbonate; acetic acid; sodium hydroxide; palladium(II) hydroxide; In methanol; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1396780-64-5
methyl 2-methyl-3-nitro-5-(trifluoromethyl)benzoate

: 1403595-59-4
C₁₅H₁₈F₃NO₂

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogen / palladium(II) hydroxide / methanol / 3 h

2.1: acetic acid / methanol / 3 h

3.1: caesium carbonate / acetonitrile / 8 h / 80 °C

4.1: sodium hydroxide; water / methanol / 1 h / 60 °C

4.2: pH 4 - 6

With water; hydrogen; caesium carbonate; acetic acid; sodium hydroxide; palladium(II) hydroxide; In methanol; acetonitrile;