C₂₂H₂₈O₂Si

Base Information

• Chemical Name: C₂₂H₂₈O₂Si
• CAS No.: 1416082-90-0
• Molecular Formula: C₂₂H₂₈O₂Si
• Molecular Weight: 352.549
• Mol file: 1416082-90-0.mol

Synonyms:C₂₂H₂₈O₂Si

Chemical Property of C₂₂H₂₈O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₈O₂Si

There total 3 articles about C₂₂H₂₈O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-4-(tert-butyldiphenylsilyl)oxy-5-hexen-1-ol (334976-46-4) → C22H28O2Si (1416082-90-0)

Guidance literature:

With sodium acetate; pyridinium chlorochromate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tetasy.2012.07.015

Reference yield:

(3RS)-6-benzyloxyhex-1-en-3-ol (126260-80-8) → C22H28O2Si (1416082-90-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: titanium(IV) isopropylate; diethyl (2S,3S)-tartrate / dichloromethane / 0.5 h / -20 °C / Molecular sieve

1.2: 6 h / -20 °C

2.1: 1H-imidazole / dichloromethane / 0 - 20 °C

3.1: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / Reflux

4.1: sodium acetate; pyridinium chlorochromate / dichloromethane / 0 - 20 °C

With 1H-imidazole; titanium(IV) isopropylate; diethyl (2S,3S)-tartrate; water; sodium acetate; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane;

DOI:10.1016/j.tetasy.2012.07.015

Reference yield:

(S)-6-(benzyloxy)hex-1-en-3-ol (334976-37-3) → C22H28O2Si (1416082-90-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 1H-imidazole / dichloromethane / 0 - 20 °C

2: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 4 h / Reflux

3: sodium acetate; pyridinium chlorochromate / dichloromethane / 0 - 20 °C

With 1H-imidazole; water; sodium acetate; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane;

DOI:10.1016/j.tetasy.2012.07.015

upstream raw materials:

(3RS)-6-benzyloxyhex-1-en-3-ol

(S)-6-(benzyloxy)hex-1-en-3-ol

(S)-4-(tert-butyldiphenylsilyl)oxy-5-hexen-1-ol

Downstream raw materials:

(S)-4-[(tert-butyldiphenylsilyl)oxy]hex-5-enoic acid