1-Hexen-3-ol, 6-(phenylmethoxy)-

Base Information

• Chemical Name: 1-Hexen-3-ol, 6-(phenylmethoxy)-
• CAS No.: 126260-80-8
• Molecular Formula: C13H18O2
• Molecular Weight: 206.285
• European Community (EC) Number: 837-136-2
• DSSTox Substance ID: DTXSID20452148
• Nikkaji Number: J1.097.438K
• Mol file: 126260-80-8.mol

Synonyms:1-Hexen-3-ol, 6-(phenylmethoxy)-;126260-80-8;6-phenylmethoxyhex-1-en-3-ol;6-(BENZYLOXY)HEX-1-EN-3-OL;6-Benzyloxy-1-hexene-3-ol;DTXSID20452148;BFA26080;EN300-7202193

Chemical Property of 1-Hexen-3-ol, 6-(phenylmethoxy)-

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 206.130679813
• Heavy Atom Count: 15
• Complexity: 162

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CC(CCCOCC1=CC=CC=C1)O

Technology Process of 1-Hexen-3-ol, 6-(phenylmethoxy)-

There total 9 articles about 1-Hexen-3-ol, 6-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

((E)-6-Benzyloxy-hex-2-enyl)-dimethyl-phenyl-silane → (3RS)-6-benzyloxyhex-1-en-3-ol (126260-80-8)

Guidance literature:

((E)-6-Benzyloxy-hex-2-enyl)-dimethyl-phenyl-silane; With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 3h;

With acetic acid; In methanol; dichloromethane; at 20 ℃; for 18h;

DOI:10.1021/ja0541074

Reference yield: 90.0%

4-benzyloxybutanal (5470-84-8) + vinyl magnesium bromide (1826-67-1) → (3RS)-6-benzyloxyhex-1-en-3-ol (126260-80-8)

Guidance literature:

In tetrahydrofuran; for 0.5h;

DOI:10.1021/jo961367i

Reference yield:

4-benzyloxybutanal (5470-84-8) + vinylmagnesium chloride (3536-96-7) → (3RS)-6-benzyloxyhex-1-en-3-ol (126260-80-8)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1055/s-0029-1216928

upstream raw materials:

4-benzyloxybutanal

vinyl magnesium bromide

4-benzyloxy-butan-1-ol

benzyl bromide

Downstream raw materials:

(4-Benzyloxy-1-vinyl-butoxymethyl)-carbamic acid cyclohexyl ester

ethyl (4E)-8-benzyloxy-4-enoctanoate

(E)-8-(benzyloxy)oct-4-enal

6-(benzyloxy)hex-1-en-3-one