alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol

Base Information

Chemical Name:alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol
CAS No.:221011-94-5
Molecular Formula:C₂₂H₂₅NO₄S
Molecular Weight:399.511
Hs Code.:
DSSTox Substance ID:DTXSID901190988

Synonyms:DTXSID901190988;alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol;221011-94-5

Suppliers and Price of alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:399.15042945
Heavy Atom Count:28
Complexity:596

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CCCCCC(C1=C(C2=CC=CC=C2N1S(=O)(=O)C3=CC=CC=C3)CO)O

Technology Process of alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol

There total 2 articles about alpha2-5-Hexen-1-yl-1-(phenylsulfonyl)-1H-indole-2,3-dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 30043-41-5
(hex-5-enyl)magnesium bromide

: 89241-34-9
1-(phenylsulfonyl)-3-(hydroxymethyl)indole-2-carboxaldehyde

: 221011-94-5
7-hydroxy-7-<1-(phenylsulfonyl)-3-(hydroxymethyl)indol-2-yl>hept-1-ene

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1080/00397919908085823

Reference yield:

: 89241-33-8
1-(phenylsulfonyl)-3-(hydroxymethyl)indole

: 221011-94-5
7-hydroxy-7-<1-(phenylsulfonyl)-3-(hydroxymethyl)indol-2-yl>hept-1-ene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LDA / 1.) THF, -78 deg C, 2 h; room temperature, 1 h, 2.) -78 deg C, 1 h

2: 72 percent / tetrahydrofuran / 1 h / 0 °C

With lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1080/00397919908085823