89241-34-9

Usage

Chemical family

Indole-2-carboxaldehyde

Functional groups

Sulfonyl, hydroxymethyl

Usage

Organic synthesis, pharmaceutical research (building block for drugs and chemical compounds, precursor for complex organic molecule synthesis)

Therapeutic potential

Treatment of various medical conditions

Upstream product

• 107-31-3 Methyl formate 
• 89241-33-8 1-(phenylsulfonyl)-3-(hydroxymethyl)indole 
• 68-12-2 N,N-dimethyl-formamide 
• 487-89-8 Indole-3-carboxaldehyde 
• 98-09-9 benzenesulfonyl chloride 
• 80360-20-9 1-(phenylsulfonyl)indole-3-carbaldehyde 

Downstream Products

• 89241-37-2 4-(phenylsulfonyl)-4H-furo<3,4-b>indole 
• 221011-94-5 7-hydroxy-7-<1-(phenylsulfonyl)-3-(hydroxymethyl)indol-2-yl>hept-1-ene 
• 239-01-0 11H-benzo[a]carbazole 
• 181212-63-5 11-(phenylsulfonyl)-11H-benzocarbazole 
• 221011-97-8 1,2,3,4-tetrahydro-11-(phenylsulfonyl)-11H-benzocarbazole 
• 221011-95-6 1-(phenylsulfonyl)-2(1-hydroxy-6-hexenyl)indole-3-carboxaldehyde 
• 221011-98-9 C₂₂H₂₁NO₃S 
• 221011-96-7 3-(5-hexenyl)-4-(phenylsulfonyl)-4H-furo<3,4-b>indole 
• 1452849-46-5 3-({[(tert-butyl)(diphenyl)silyl]oxy}methyl)-1-(phenylsulfonyl)-1H-indole-2-carboxaldehyde 
• 89241-40-7 5-(phenylsulfonyl)-6,11-epoxy-6,11-dihydro-5H-benzocarbazole 

Relevant academic research and scientific papers

Intramolecular Diels-Alder reactions of 4H-furo[3,4-b]indoles. New syntheses of benzo[a]carbazoles and benzo[c]carbazoles

Furoindoles 7 and 16 undergo smooth intramolecular Diels-Alder reactions to afford, after dehydration, hydrolysis, and oxidation, benzocarbazoles 11 and 21, respectively.

4-(PHENYLSULFONYL)-4H-FUROINDOLE - A STABLE SYNTHETIC ANALOGUE OF INDOLE-2,3-QUINODIMETHANE

The N-phenylsulfonyl derivate (2) of the previously unknown fused heterocycle 4H-furo indole is synthesized from indole-3-carboxaldehyde (3) in 28percent yield and undergoes a Diels-Alder reaction with benzyne to give 5H-benzocarbazole (11) in 33percent yield after deoxygenation and deprotection.