tert-Butyl (2-amino-5-methylphenyl)carbamate

Base Information

Chemical Name:tert-Butyl (2-amino-5-methylphenyl)carbamate
CAS No.:885270-77-9
Molecular Formula:C12H18 N2 O2
Molecular Weight:222.287
Hs Code.:2924299090
European Community (EC) Number:809-540-9
DSSTox Substance ID:DTXSID40697615
Wikidata:Q82627554
Mol file:885270-77-9.mol

Synonyms:885270-77-9;tert-Butyl (2-amino-5-methylphenyl)carbamate;(2-AMINO-5-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;tert-butyl N-(2-amino-5-methylphenyl)carbamate;SCHEMBL3407965;DTXSID40697615;MFCD05663965;AKOS024258385;AB22077;CS-0326104;FT-0716523;tert-Butyl(2-amino-5-methylphenyl)carbamate;(2-Amino-5-methyl-phenyl)-carbamic acid t-butyl ester;(2-Amino-5-methyl-phenyl)-carbamic acid tert-butyl ester, AldrichCPR

Suppliers and Price of tert-Butyl (2-amino-5-methylphenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2-Amino-5-methyl-phenyl)-carbamicAcidtert-butylester
10mg
$ 45.00

J&W Pharmlab
(2-Amino-5-methyl-phenyl)-carbamicacidtert-butylester 97%
1g
$ 198.00

J&W Pharmlab
(2-Amino-5-methyl-phenyl)-carbamicacidtert-butylester 97%
500mg
$ 149.00

J&W Pharmlab
(2-Amino-5-methyl-phenyl)-carbamicacidtert-butylester 97%
250mg
$ 123.00

J&W Pharmlab
(2-Amino-5-methyl-phenyl)-carbamicacidtert-butylester 97%
5g
$ 798.00

Crysdot
tert-Butyl(2-amino-5-methylphenyl)carbamate 95+%
5g
$ 672.00

American Custom Chemicals Corporation
(2-AMINO-5-METHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 505.08

Alichem
tert-Butyl(2-amino-5-methylphenyl)carbamate
5g
$ 552.47

AK Scientific
(2-Amino-5-methyl-phenyl)-carbamicacidtert-butylester
5g
$ 2131.00

Total 12 raw suppliers

Chemical Property of tert-Butyl (2-amino-5-methylphenyl)carbamate

Chemical Property:

PSA：64.35000
LogP:3.57840
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:222.136827821
Heavy Atom Count:16
Complexity:248

Purity/Quality:

97% ^*data from raw suppliers

(2-Amino-5-methyl-phenyl)-carbamicAcidtert-butylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)N)NC(=O)OC(C)(C)C

Technology Process of tert-Butyl (2-amino-5-methylphenyl)carbamate

There total 6 articles about tert-Butyl (2-amino-5-methylphenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 496-72-0
4-methyl-1,2-diaminobenzene

: 885270-81-5
4-N-(tert-butoxycarbonyl)-3,4-diaminotoluene

: 885270-77-9
3-N-(tert-butoxycarbonyl)-3,4-diaminotoluene

Guidance literature:: In dichloromethane; water; at 20 ℃;

Reference yield:

: tert-butyl (5-methyl-2-nitrophenyl)carbamate

: 885270-77-9
3-N-(tert-butoxycarbonyl)-3,4-diaminotoluene

Guidance literature:: With tin(ll) chloride; In N,N-dimethyl-formamide; at 50 ℃; for 1.5h; Inert atmosphere;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 885270-77-9
3-N-(tert-butoxycarbonyl)-3,4-diaminotoluene

Guidance literature:: Multi-step reaction with 3 steps

1.1: dmap / tetrahydrofuran / 1.5 h / 20 °C

1.2: 22 h / 65 °C

2.1: dihydroxyborane; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; 1,2-dimethoxyethane / 20 h / 110 °C / Inert atmosphere

3.1: tin(ll) chloride / N,N-dimethyl-formamide / 1.5 h / 50 °C / Inert atmosphere

With dmap; dihydroxyborane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; tin(ll) chloride; In tetrahydrofuran; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide;