7,8-dihydroxy-3'-carboxyisoflavone

Base Information

• Chemical Name: 7,8-dihydroxy-3'-carboxyisoflavone
• CAS No.: 116718-77-5
• Molecular Formula: C₁₆H₁₀O₆
• Molecular Weight: 298.252
• Mol file: 116718-77-5.mol

Synonyms:7,8-dihydroxy-3'-carboxyisoflavone

Chemical Property of 7,8-dihydroxy-3'-carboxyisoflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,8-dihydroxy-3'-carboxyisoflavone

There total 4 articles about 7,8-dihydroxy-3'-carboxyisoflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 2,3,4-trihydroxy-3'-carboxybenzylketone (116743-80-7) → 7,8-dihydroxy-3'-carboxyisoflavone (116718-77-5)

Guidance literature:

With boron trifluoride diethyl etherate; methanesulfonyl chloride; at 100 ℃; for 2h;

DOI:10.1081/SCC-100104346

Reference yield:

2,3,4-trihydroxy-3'-carboxybenzylketone (116743-80-7) → 7,8-dihydroxy-3'-carboxyisoflavone (116718-77-5)

Guidance literature:

Reference yield:

ethyl 3-cyanomethylbenzoate (5689-33-8) → 7,8-dihydroxy-3'-carboxyisoflavone (116718-77-5)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl; ZnCl₂ / diethyl ether / 0 - 20 °C

2: 5 percent HCl / 5 h / Heating

3: 75 percent / BF₃*Et₂O; MeSO₂Cl / 2 h / 100 °C

With hydrogenchloride; boron trifluoride diethyl etherate; methanesulfonyl chloride; zinc(II) chloride; In diethyl ether;

DOI:10.1081/SCC-100104346

upstream raw materials:

N,N-dimethyl-formamide

2,3,4-trihydroxy-3'-carboxybenzylketone

ethyl 3-cyanomethylbenzoate