2,3,4-trihydroxy-3'-carboxybenzylketone

Base Information

• Chemical Name: 2,3,4-trihydroxy-3'-carboxybenzylketone
• CAS No.: 116743-80-7
• Molecular Formula: C₁₅H₁₂O₆
• Molecular Weight: 288.257
• Mol file: 116743-80-7.mol

Synonyms:2,3,4-trihydroxy-3'-carboxybenzylketone

Chemical Property of 2,3,4-trihydroxy-3'-carboxybenzylketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-trihydroxy-3'-carboxybenzylketone

There total 3 articles about 2,3,4-trihydroxy-3'-carboxybenzylketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-cyanomethylbenzoate (5689-33-8) → 2,3,4-trihydroxy-3'-carboxybenzylketone (116743-80-7)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl; ZnCl₂ / diethyl ether / 0 - 20 °C

2: 5 percent HCl / 5 h / Heating

With hydrogenchloride; zinc(II) chloride; In diethyl ether;

DOI:10.1081/SCC-100104346

Reference yield:

ethanol (64-17-5) + 3-[2-imino-2-(2,3,4-trihydroxy-phenyl)-ethyl]-benzoic acid; hydrochloride → 2,3,4-trihydroxy-3'-carboxybenzylketone (116743-80-7) + 3-[2-oxo-2-(2,3,4-trihydroxy-phenyl)-ethyl]-benzoic acid ethyl ester

Guidance literature:

With hydrogenchloride; for 5h; Heating;

DOI:10.1081/SCC-100104346

Reference yield:

→ 2,3,4-trihydroxy-3'-carboxybenzylketone (116743-80-7)

Guidance literature:

upstream raw materials:

ethanol

ethyl 3-cyanomethylbenzoate

Downstream raw materials:

7,8-dihydroxy-3'-carboxyisoflavone