3-(4-chlorophenyl)-1-methyl-1H-pyrazole

Base Information

Chemical Name:3-(4-chlorophenyl)-1-methyl-1H-pyrazole
CAS No.:73387-53-8
Molecular Formula:C₁₀H₉ClN₂
Molecular Weight:192.648
Hs Code.:
DSSTox Substance ID:DTXSID301280119

Synonyms:3-(4-chlorophenyl)-1-methyl-1H-pyrazole;73387-53-8;SCHEMBL2615403;DTXSID301280119

Suppliers and Price of 3-(4-chlorophenyl)-1-methyl-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-chlorophenyl)-1-methyl-1H-pyrazole

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:192.0454260
Heavy Atom Count:13
Complexity:166

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C=CC(=N1)C2=CC=C(C=C2)Cl

Technology Process of 3-(4-chlorophenyl)-1-methyl-1H-pyrazole

There total 5 articles about 3-(4-chlorophenyl)-1-methyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 41555-47-9
1-(4-chlorobenzylidene)-2-methylhydrazine

: 107-06-2,52399-93-6
1,2-dichloro-ethane

: 73387-53-8
3-(4'-chlorophenyl)-1-methylpyrazole

Guidance literature:: With sodium nitrite; In ethanol; at 110 ℃; for 24h; Sealed tube;
DOI:10.1016/j.cclet.2021.02.025

Reference yield:

: 33994-12-6
3-bromo-1-(4-chlorophenyl)propan-1-one

: 73387-53-8
3-(4'-chlorophenyl)-1-methylpyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate / propan-1-ol; water / 5 h / Reflux

1.2: 22 h / Reflux

2.1: manganese(IV) oxide / toluene / 24 h / Reflux

With manganese(IV) oxide; sodium carbonate; In propan-1-ol; water; toluene;
DOI:10.1016/j.tet.2019.130920