Tert-butyl 3-(piperidin-4-YL)propylcarbamate

Base Information

Chemical Name:Tert-butyl 3-(piperidin-4-YL)propylcarbamate
CAS No.:885268-87-1
Molecular Formula:C₁₃H₂₆N₂O₂
Molecular Weight:242.362
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80700576
Wikidata:Q82631993
Mol file:885268-87-1.mol

Synonyms:885268-87-1;TERT-BUTYL 3-(PIPERIDIN-4-YL)PROPYLCARBAMATE;tert-butyl N-(3-piperidin-4-ylpropyl)carbamate;tert-Butyl N-[3-(piperidin-4-yl)propyl]carbamate;Carbamic acid,[3-(4-piperidinyl)propyl]-, 1,1-dimethylethyl ester (9CI);SCHEMBL16023429;DTXSID80700576;4-[3-(Boc-amino)propyl]piperidine;MB05452;FT-0763943;F80138;tert-Butyl [3-(piperidin-4-yl)propyl]carbamate;J-524502

Suppliers and Price of Tert-butyl 3-(piperidin-4-YL)propylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-3-(PIPERIDIN-4-YL)PROPYLCARBAMATE 98.00%
5MG
$ 502.52

Activate Scientific
4-[3-(Boc-amino)propyl]piperidine 97%
1 g
$ 743.00

Acrotein
4-[3-(Boc-amino)propyl]piperidine 97%
0.5g
$ 366.67

Acrotein
4-[3-(Boc-amino)propyl]piperidine 97%
0.25g
$ 247.50

Total 2 raw suppliers

Chemical Property of Tert-butyl 3-(piperidin-4-YL)propylcarbamate

Chemical Property:

PSA：53.85000
LogP:2.82410
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:242.199428076
Heavy Atom Count:17
Complexity:230

Purity/Quality:

99% ^*data from raw suppliers

TERT-BUTYL-3-(PIPERIDIN-4-YL)PROPYLCARBAMATE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCCC1CCNCC1

Technology Process of Tert-butyl 3-(piperidin-4-YL)propylcarbamate

There total 12 articles about Tert-butyl 3-(piperidin-4-YL)propylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1-benzyl-4-(3-N-(tert-butoxycarbonyl)aminopropyl)piperidine

: 885268-87-1
4-(3-N-tert-butoxycarbonylaminopropyl)piperidine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 22h; under 60.006 Torr;
DOI:10.1016/j.bmc.2015.01.015

Reference yield: 50.0%

: 164648-58-2
tert-butyl (3-(pyridine-4-yl)propyl)carbamate

: 885268-87-1
4-(3-N-tert-butoxycarbonylaminopropyl)piperidine

Guidance literature:: With platinum(IV) oxide; hydrogen; In acetic acid; at 40 ℃; for 12h; under 2585.81 Torr;
DOI:10.1021/jm400204k

Reference yield:

: 2629-72-3
4-(3-Hydroxypropyl)pyridine

: 885268-87-1
4-(3-N-tert-butoxycarbonylaminopropyl)piperidine

Guidance literature:: Multi-step reaction with 4 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

2: hydrazine hydrate / methanol / 18 h / 20 °C

3: triethylamine / tetrahydrofuran / 20 °C

4: platinum(IV) oxide; hydrogen / acetic acid / 12 h / 40 °C / 2585.81 Torr

With platinum(IV) oxide; di-isopropyl azodicarboxylate; hydrogen; hydrazine hydrate; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; acetic acid;
DOI:10.1021/jm400204k