4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE

Base Information

• Chemical Name: 4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE
• CAS No.: 164648-58-2
• Molecular Formula: C13H20N2O2
• Molecular Weight: 236.314
• Hs Code.: 2933399090
• Mol file: 164648-58-2.mol

Synonyms:4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE;4-TERT-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE;

Chemical Property of 4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE

Chemical Property:

• Boiling Point: 375.7±25.0 °C(Predicted)
• PKA: 12.71±0.46(Predicted)
• PSA: 51.22000
• Density: 1.041±0.06 g/cm3(Predicted)
• LogP: 2.92980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

N-Boc-3-(4-pyridyl)propylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE

There total 1 articles about 4-T-BUTYLOXYCARBONYL-AMINOPROPYL-PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-vinylpyridine (100-43-6,329041-72-7) + potassium tert-butyl N-[(trifluorolambda-4-boranyl)methyl]carbamate (1314538-55-0) → tert-butyl (3-(pyridine-4-yl)propyl)carbamate (164648-58-2)

Guidance literature:

With [Ir(5-(trifluoromethyl)-2-(2,4-difluorophenyl)pyridine)₂(2,2'-bipyridine)](PF₆); In methanol; acetone; at 20 ℃; for 24h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1002/adsc.201400556

Reference yield: 50.0%

tert-butyl (3-(pyridine-4-yl)propyl)carbamate (164648-58-2) → 4-(3-N-tert-butoxycarbonylaminopropyl)piperidine (885268-87-1)

Guidance literature:

With platinum(IV) oxide; hydrogen; In acetic acid; at 40 ℃; for 12h; under 2585.81 Torr;

DOI:10.1021/jm400204k

upstream raw materials:

4-vinylpyridine

potassium tert-butyl N-[(trifluorolambda-4-boranyl)methyl]carbamate

Downstream raw materials:

4-(3-N-tert-butoxycarbonylaminopropyl)piperidine

Refernces