C₄₆H₄₆N₆O₉

Base Information

• Chemical Name: C₄₆H₄₆N₆O₉
• CAS No.: 1341219-85-9
• Molecular Formula: C₄₆H₄₆N₆O₉
• Molecular Weight: 826.906
• Mol file: 1341219-85-9.mol

Synonyms:C₄₆H₄₆N₆O₉

Chemical Property of C₄₆H₄₆N₆O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₆H₄₆N₆O₉

There total 3 articles about C₄₆H₄₆N₆O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C54H54N6O11 (1341219-79-1) → C46H46N6O9 (1341219-85-9)

Guidance literature:

With water; cesium fluoride; In 1,4-dioxane; for 21h; Reflux;

DOI:10.1021/jo201495w

Reference yield:

C66H82N6O11Si2 (1341219-75-7) → C46H46N6O9 (1341219-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C

2: water; cesium fluoride / 1,4-dioxane / 21 h / Reflux

With tetrabutyl ammonium fluoride; water; cesium fluoride; In tetrahydrofuran; 1,4-dioxane;

DOI:10.1021/jo201495w

Reference yield:

N-(3-allyl-4-methoxy-2,5-bis-methoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl) (E)-3-O-allyl-1-(6-amino-N6-trityl-9H-purin-9-yl)-2-O-tert-butyldimethylsilyl-5,6-dideoxy-β-D-ribo-5-eneheptofuranuronamide (1341219-71-3) → C46H46N6O9 (1341219-85-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Grubbs catalyst first generation / dichloromethane / 5 h / Reflux

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C

3: water; cesium fluoride / 1,4-dioxane / 21 h / Reflux

With Grubbs catalyst first generation; tetrabutyl ammonium fluoride; water; cesium fluoride; In tetrahydrofuran; 1,4-dioxane; dichloromethane;

DOI:10.1021/jo201495w

upstream raw materials:

N-(3-allyl-4-methoxy-2,5-bis-methoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl) (E)-3-O-allyl-1-(6-amino-N6-trityl-9H-purin-9-yl)-2-O-tert-butyldimethylsilyl-5,6-dideoxy-β-D-ribo-5-eneheptofuranuronamide

C₆₆H₈₂N₆O₁₁Si₂

C₅₄H₅₄N₆O₁₁