Technology Process of C30H33FN4O5
There total 5 articles about C30H33FN4O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
for 4h;
DOI:10.1016/j.bmc.2011.12.045
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C
1.2: 2.5 h / 0 °C
2.1: trichlorophosphate / 0.33 h / 0 °C
2.2: 1.5 h / 0 - 20 °C
2.3: Cooling with ice
3.1: ethanol / 22 h
3.2: 1 h
4.1: sodium hydroxide / tetrahydrofuran / 4 h / 20 °C
5.1: dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 4 h
With
dmap; sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; trichlorophosphate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; mineral oil;
2.2: Vilsmeier-Haack reaction;
DOI:10.1016/j.bmc.2011.12.045
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide / tetrahydrofuran / 4 h / 20 °C
2: dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 4 h
With
dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.12.045