1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione

Base Information

Chemical Name:1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione
CAS No.:1205548-02-2
Molecular Formula:C₁₉H₂₁NO₅
Molecular Weight:343.379
Hs Code.:
Mol file:1205548-02-2.mol

Synonyms:1-(4-(dimethylamino)phenyl)-3-(2-hydroxy-3,4-dimethoxyphenyl)propane-1,3-dione

Suppliers and Price of 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione
500mg
$ 1320.00

TRC
1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione
50mg
$ 165.00

Medical Isotopes, Inc.
1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione
500 mg
$ 2200.00

Total 2 raw suppliers

Chemical Property of 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione

Chemical Property:

Solubility.:Dichloromethane, Methanol

Purity/Quality:

99% ^*data from raw suppliers

1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione is a reactant used in the preparation of 7,8-Dihydroxyflavone (D452830) derivatives which promote neurogenesis and exhibits potent antidepressant effect.

Technology Process of 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione

There total 3 articles about 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1205548-01-1
6-acetyl-2,3-dimethoxyphenyl 4-(dimethylamino)benzoate

: 1205548-02-2
1-(4-(dimethylamino)phenyl)-3-(2-hydroxy-3,4-dimethoxyphenyl)propane-1,3-dione

Guidance literature:: With pyridine; potassium hydroxide; at 50 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm101206p

Reference yield:

: 4755-50-4
4-(dimethylamino)benzoyl chloride

: 1205548-02-2
1-(4-(dimethylamino)phenyl)-3-(2-hydroxy-3,4-dimethoxyphenyl)propane-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C

2: pyridine; potassium hydroxide / 12 h / 50 °C

With pyridine; potassium hydroxide; In dichloromethane; 2: |Baker-Venkataraman Rearrangement;
DOI:10.1016/j.bmc.2013.10.012

Reference yield:

: 5396-18-9
2'-hydroxy-3',4'-dimethoxyacetophenone

: 1205548-02-2
1-(4-(dimethylamino)phenyl)-3-(2-hydroxy-3,4-dimethoxyphenyl)propane-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C

2: pyridine; potassium hydroxide / 12 h / 50 °C

With pyridine; potassium hydroxide; In dichloromethane; 2: |Baker-Venkataraman Rearrangement;
DOI:10.1016/j.bmc.2013.10.012