methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Base Information

Chemical Name:methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose
CAS No.:264622-13-1
Molecular Formula:C₂₀H₂₈INO₆
Molecular Weight:505.35
Hs Code.:

Synonyms:methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Suppliers and Price of methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

There total 4 articles about methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 264622-12-0
methyl [7-(benzyloxycarbonyl)amino-5,6,7-trideoxy-2,3-O-(isopropylidene)]-β-D-octaribofuranose

: 264622-13-1
methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Guidance literature:: With methyltriphenoxyphosphonium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

: 21149-17-7
methyl 2-(benzyloxycarbonylamino)acrylate

: 264622-13-1
methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / CuI; Zn powder / tetrahydrofuran; H₂O

2: 85 percent / LiCl; NaBH₄ / tetrahydrofuran / 0.05 h / 0 °C

3: 75 percent / methyltriphenoxyphosphonium iodide / dimethylformamide / 18 h / 20 °C

With sodium tetrahydroborate; copper(l) iodide; methyltriphenoxyphosphonium iodide; lithium chloride; zinc; In tetrahydrofuran; water; N,N-dimethyl-formamide; 1: Addition / 2: Reduction / 3: Iodination;

Reference yield:

: 38838-06-1
methyl 5-deoxy-5-iodo-2,3-isopropylidene-β-D-ribofuranoside

: 264622-13-1
methyl [7-(benzyloxycarbonyl)amino-5,6,7,8-tetradeoxy-8-iodo-2,3-O-(isopropylidene)]-β-D-octaribofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / CuI; Zn powder / tetrahydrofuran; H₂O

2: 85 percent / LiCl; NaBH₄ / tetrahydrofuran / 0.05 h / 0 °C

3: 75 percent / methyltriphenoxyphosphonium iodide / dimethylformamide / 18 h / 20 °C

With sodium tetrahydroborate; copper(l) iodide; methyltriphenoxyphosphonium iodide; lithium chloride; zinc; In tetrahydrofuran; water; N,N-dimethyl-formamide; 1: Addition / 2: Reduction / 3: Iodination;