Technology Process of 2-(1,3-dithian-2-yl)-4-nitrophenol
There total 1 articles about 2-(1,3-dithian-2-yl)-4-nitrophenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.bmc.2012.02.001
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: acetic acid; zinc / 1 h / 20 °C
2.1: acetic acid; sodium nitrite / water / 2 h / 0 °C
2.2: 0.5 h / 0 - 20 °C
3.1: 36 h / 20 °C / Inert atmosphere; Neat (no solvent)
3.2: 24 h / 20 °C / Inert atmosphere
4.1: diethylamino-sulfur trifluoride / dichloromethane / 3 h / 20 °C / Inert atmosphere
5.1: sodium methylate / methanol / 2 h / 20 °C / Inert atmosphere
5.2: 20 °C / Inert atmosphere
6.1: sodium hydroxide / water / 1 h / 20 °C
6.2: 20 °C
7.1: copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / water; dimethyl sulfoxide / 8 h
With
diethylamino-sulfur trifluoride; sodium methylate; copper(II) sulfate; acetic acid; sodium L-ascorbate; sodium hydroxide; zinc; sodium nitrite; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2012.02.001
