(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Base Information

Chemical Name:(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene
CAS No.:596792-50-6
Molecular Formula:C₅₁H₇₀O₉SSi₂
Molecular Weight:915.348
Hs Code.:

(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Synonyms:(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Suppliers and Price of (2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

There total 4 articles about (2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-Butyl-[(2R,3S)-2-methyl-3-(toluene-4-sulfonyl)-oxiranylmethoxy]-diphenyl-silane

: Trifluoro-methanesulfonic acid (2R,4aR,6S,7R,9R,10aS)-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocycloocten-6-ylmethyl ester

: 596792-50-6
(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Guidance literature:: With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; at -100 ℃; for 0.666667h;
DOI:10.1021/jo049877x

Reference yield:

: tert-Butyl-[(2R,3R)-2-methyl-3-(toluene-4-sulfonyl)-oxiranylmethoxy]-diphenyl-silane

: Trifluoro-methanesulfonic acid (2R,4aR,6S,7R,9R,10aS)-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocycloocten-6-ylmethyl ester

: 596792-50-6
(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Guidance literature:: With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at -110 ℃; for 0.5h;
DOI:10.1016/S0040-4039(03)01214-0

Reference yield:

: 79271-56-0
triethylsilyl trifluoromethyl sulfonate

: 596792-50-6
(2R,4aR,6S,7R,9R,10aS)-6-[(2S,3R)-3-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methyl-2-(toluene-4-sulfonyl)-oxiranylmethyl]-2-(4-methoxy-phenyl)-9-methyl-7-triethylsilanyloxy-octahydro-1,3,5-trioxa-benzocyclooctene

Guidance literature:: Multi-step reaction with 2 steps

1.1: 2,6-lutidine / CH₂Cl₂ / 0.42 h / -78 °C

1.2: CH₂Cl₂ / 0.5 h / -78 °C

2.1: n-BuLi / hexamethylphosphoric acid triamide; tetrahydrofuran; hexane / 0.67 h / -100 °C

With 2,6-dimethylpyridine; n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; dichloromethane;
DOI:10.1021/jo049877x