6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid

Base Information

Chemical Name:6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid
CAS No.:883241-16-5
Molecular Formula:C14H10 F3 N O2
Molecular Weight:281.234
Hs Code.:
Mol file:883241-16-5.mol

Synonyms:2-[(4-Trifluoromethyl)phenyl]-6-methylnicotinic Acid;6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid

Suppliers and Price of 6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[(4-Trifluoromethyl)phenyl]-6-methylNicotinicAcid
50mg
$ 155.00

American Custom Chemicals Corporation
2-((4-TRIFLUOROMETHYL)PHENYL)-6-METHYL NICOTINIC ACID 95.00%
500MG
$ 1871.10

American Custom Chemicals Corporation
2-((4-TRIFLUOROMETHYL)PHENYL)-6-METHYL NICOTINIC ACID 95.00%
50MG
$ 739.20

Total 2 raw suppliers

Chemical Property of 6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-[(4-Trifluoromethyl)phenyl]-6-methylNicotinicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Shows MTP inhibitory effects Shows MTP inhibitory effects.

Technology Process of 6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid

There total 4 articles about 6-Methyl-2-[4-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₁₆H₁₄F₃NO₂

: 883241-16-5
6-methyl-2-(4-trifluoromethylphenyl)nicotinic acid

Guidance literature:: With water; sodium hydroxide; In methanol; at 20 ℃; for 3h;

Reference yield:

: 883241-15-4
6-Methyl-2-(4-trifluoromethylphenyl)nicotinic acid methyl ester

: 883241-16-5
6-methyl-2-(4-trifluoromethylphenyl)nicotinic acid

Guidance literature:: 6-Methyl-2-(4-trifluoromethylphenyl)nicotinic acid methyl ester; With sodium hydroxide; water; In methanol; at 0 - 45 ℃; for 3h;

With hydrogenchloride; In methanol; water; at 0 ℃; pH=3;

Reference yield:

: 39073-14-8
ethyl 2-chloro-6-methyl-3-pyridinecarboxylate

: 883241-16-5
6-methyl-2-(4-trifluoromethylphenyl)nicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 4 h / Reflux

2: sodium hydroxide; water / methanol / 3 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; potassium carbonate; sodium hydroxide; In methanol; toluene;