2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate

Base Information

• Chemical Name: 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate
• CAS No.: 1313526-69-0
• Molecular Formula: CF₃O₃S*C₃₀H₂₄ClN₂
• Molecular Weight: 597.057
• Mol file: 1313526-69-0.mol

Synonyms:2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate

Chemical Property of 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate

There total 9 articles about 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C30H23ClN2 → 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate (1313526-69-0)

Guidance literature:

With silver trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1039/c1ob05258f

Reference yield:

2-bromo-9H-carbazole (3652-90-2) → 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate (1313526-69-0)

Guidance literature:

Multi-step reaction with 7 steps

1.1: potassium hydroxide / acetone / 0.5 h / Reflux

1.2: 1 h / Reflux

2.1: trichlorophosphate / 0 - 70 °C

3.1: hydrazine hydrate; potassium hydroxide / ethylene glycol / 3 h / 200 °C

4.1: trichlorophosphate / N,N-dimethyl-formamide / 0 - 70 °C

5.1: triethylamine / tetrahydrofuran / 0.17 h / 20 °C / Molecular sieve; Inert atmosphere

5.2: 4 h / Molecular sieve; Inert atmosphere; Heating

6.1: magnesium sulfate / dichloromethane / Reflux

7.1: silver trifluoromethanesulfonate / dichloromethane / 1 h / 20 °C

With silver trifluoromethanesulfonate; magnesium sulfate; hydrazine hydrate; triethylamine; potassium hydroxide; trichlorophosphate; In tetrahydrofuran; dichloromethane; ethylene glycol; N,N-dimethyl-formamide; acetone; 2.1: Vilsmeier formylation / 3.1: Wolff-Kishner reduction / 4.1: Vilsmeier formylation / 5.1: Sonogashira coupling / 5.2: Sonogashira coupling;

DOI:10.1039/c1ob05258f

Reference yield:

phenylboronic acid (98-80-6) → 2-(4-chlorophenyl)-6-ethyl-9-methyl-3-phenyl-6H-pyrido[4,3-b]carbazol-2-ium triflate (1313526-69-0)

Guidance literature:

Multi-step reaction with 9 steps

1.1: palladium diacetate; potassium carbonate; triphenylphosphine / water; toluene / 8 h / 70 °C

2.1: triethyl phosphite / 5 h / Reflux

3.1: potassium hydroxide / acetone / 0.5 h / Reflux

3.2: 1 h / Reflux

4.1: trichlorophosphate / 0 - 70 °C

5.1: hydrazine hydrate; potassium hydroxide / ethylene glycol / 3 h / 200 °C

6.1: trichlorophosphate / N,N-dimethyl-formamide / 0 - 70 °C

7.1: triethylamine / tetrahydrofuran / 0.17 h / 20 °C / Molecular sieve; Inert atmosphere

7.2: 4 h / Molecular sieve; Inert atmosphere; Heating

8.1: magnesium sulfate / dichloromethane / Reflux

9.1: silver trifluoromethanesulfonate / dichloromethane / 1 h / 20 °C

With silver trifluoromethanesulfonate; palladium diacetate; magnesium sulfate; potassium carbonate; hydrazine hydrate; triethylamine; triphenylphosphine; potassium hydroxide; triethyl phosphite; trichlorophosphate; In tetrahydrofuran; dichloromethane; water; ethylene glycol; N,N-dimethyl-formamide; acetone; toluene; 1.1: Suzuki coupling / 4.1: Vilsmeier formylation / 5.1: Wolff-Kishner reduction / 6.1: Vilsmeier formylation / 7.1: Sonogashira coupling / 7.2: Sonogashira coupling;

DOI:10.1039/c1ob05258f

upstream raw materials:

7-bromo-9-ethyl-9H-carbazole-3-carbaldehyde

2-bromo-9-ethyl-6-methyl-9H-carbazole-3-carbaldehyde

9-ethyl-6-methyl-2-(2-phenylethynyl)-9H-carbazole-3-carbaldehyde

2-bromo-9-ethyl-6-methyl-9H-carbazole