allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate

Base Information

• Chemical Name: allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate
• CAS No.: 911807-84-6
• Molecular Formula: C₃₃H₃₂O₁₁
• Molecular Weight: 604.61
• Mol file: 911807-84-6.mol

Synonyms:allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate

Chemical Property of allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate

There total 1 articles about allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

prop-2-enyl-3-hydroxy-6-methoxybenzofuran-2-carboxylate (132835-27-9) + 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal (119529-69-0) → allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate (911807-84-6)

Guidance literature:

With lead(IV) acetate; n-butyllithium; trimethyltin(IV)chloride; mercury(II) diacetate; Yield given. Multistep reaction;

DOI:10.1039/P19940001791

Reference yield: 92.0%

allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate (911807-84-6) → 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-2,3-dihydrobenzofuran-3-one (911798-58-8)

Guidance literature:

With palladium diacetate; formic acid; triethylamine; triphenylphosphine; In tetrahydrofuran; for 96h; Ambient temperature;

DOI:10.1039/P19940001791

Reference yield:

allyl 2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-3-oxobenzofuran-2-carboxylate (911807-84-6) → 5,7-dimethoxy-8-(6-methoxy-3-oxo-2,3-2,3-dihydrobenzofuran-2-yl)-2-(3-methoxyphenyl)chroman-4-one

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / Ph₃P, Pd(OAc)2, HCO₂H, Et₃N / tetrahydrofuran / 96 h / Ambient temperature

2: 92 percent / aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature

With hydrogenchloride; palladium diacetate; formic acid; triethylamine; triphenylphosphine; In tetrahydrofuran;

DOI:10.1039/P19940001791

upstream raw materials:

prop-2-enyl-3-hydroxy-6-methoxybenzofuran-2-carboxylate

8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal

Downstream raw materials:

2-(5,7-dimethoxy-2-(4-methoxyphenyl)spirodioxolan-8-yl>)-6-methoxy-2,3-dihydrobenzofuran-3-one