8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal

Base Information

• Chemical Name: 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal
• CAS No.: 119529-69-0
• Molecular Formula: C₂₀H₂₁BrO₆
• Molecular Weight: 437.287
• Mol file: 119529-69-0.mol

Synonyms:8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal

Chemical Property of 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal

There total 4 articles about 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

8-bromo-4',5,7-trimethoxyflavanone (119529-70-3) + ethylene glycol (107-21-1) → 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal (119529-69-0)

Guidance literature:

With Amberlit IR-120 (H+ form); orthoformic acid triethyl ester; at 90 ℃; for 0.5h;

Reference yield: 72.0%

5,7,4'-Trimethoxyflavanon-ethylenacetal (119529-68-9) → 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal (119529-69-0)

Guidance literature:

With N-Bromosuccinimide; In tetrachloromethane; at 80 ℃; for 1h;

Reference yield:

4',5,7-trimethoxyflavanone (66074-95-1,38302-15-7) → 8-bromo-4',5,7-trimethoxy-flavanone ethylene ketal (119529-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / HC(OEt)3, Amberlit IR-120 (H+ form) / 0.5 h / 90 °C

2: 72 percent / N-bromosuccinimide / CCl₄ / 1 h / 80 °C

With N-Bromosuccinimide; Amberlit IR-120 (H+ form); orthoformic acid triethyl ester; In tetrachloromethane;

upstream raw materials:

8-bromo-4',5,7-trimethoxyflavanone

ethylene glycol

5,7,4'-Trimethoxyflavanon-ethylenacetal

4',5,7-trimethoxyflavanone

Downstream raw materials:

5,7,4’-O,O,O-trimethoxy-8-methylnaringenin

5,7-dimethoxy-2-(4''-methoxyphenyl)-8-(trimethylstannyl)-spiro(chromane-4,2'-[1,3]dioxolane)

5,7-dimethoxy-2-(4-methoxyphenyl)-8-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-4H-1-benzopyran-4-one

5,7,4'-Trimethoxy-8-(2,3,5,6-tetra-O-acetyl-D-glucofuranosyl)flavon