2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

Base Information

Chemical Name:2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid
CAS No.:1233517-64-0
Molecular Formula:C₄₅H₄₂N₄O₅
Molecular Weight:718.852
Hs Code.:

Synonyms:2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

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Chemical Property of 2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

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Technology Process of 2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

There total 2 articles about 2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₄₅H₄₁N₄O₅Pol

: 1233517-64-0
2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.666667h; Wang resin Automated synthesizer;
DOI:10.1016/j.bmc.2012.09.053

Reference yield:

: Fmoc-gly-wang resin

: 1219921-24-0
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(benzyl)amino)benzoic acid

: 1233518-05-2
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(isobutyl)amino)benzoic acid

: 1233518-06-3
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(naphthalen-2-ylmethyl)amino)benzoic acid

: 1233517-64-0
2-(4-(4-(4-(benzylamino)-N-(naphthalen-2-ylmethyl)benzamido)-N-isobutylbenzamido)benzamido)acetic acid

Guidance literature:: 4-((((9H-fluoren-9-yl)methoxy)carbonyl)(isobutyl)amino)benzoic acid; With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In chloroform; at 20 ℃; for 3h; Sealed flask;

Fmoc-gly-wang resin; With piperidine; In dichloromethane; N,N-dimethyl-formamide; solid phase reaction;

4-((((9H-fluoren-9-yl)methoxy)carbonyl)(benzyl)amino)benzoic acid; 4-((((9H-fluoren-9-yl)methoxy)carbonyl)(naphthalen-2-ylmethyl)amino)benzoic acid; Further stages;
DOI:10.1039/c001164a