(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

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Chemical Name:(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid
CAS No.:1330003-28-5
Molecular Formula:C₂₅H₃₁N₉O₇
Molecular Weight:569.577
Hs Code.:

Synonyms:(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

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Chemical Property of (S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

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Technology Process of (S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

There total 2 articles about (S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 881171-52-4
(S)-6-(4-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanamido)hexanoic acid

: 1330003-28-5
(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

Guidance literature:: With hydroxylamine; In N,N-dimethyl-formamide; at 0 ℃; for 17h; Inert atmosphere;
DOI:10.2174/157340611796150923

Reference yield:

: 59-30-3
(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)pentanedioic acid

: 60-32-2,93208-38-9
6-aminohexanoic acid

: 1330003-28-5
(S)-2-(4-(((2-amino-4-hydroxypteridin-6-yl)methyl)amino)benzamido)-5-((6-(hydroxyamino)-6-oxohexyl)amino)-5-oxopentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetra fluoroborate / N,N-dimethyl-formamide / 14 h / 0 - 20 °C / Inert atmosphere

2: hydroxylamine / N,N-dimethyl-formamide / 17 h / 0 °C / Inert atmosphere

With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetra fluoroborate; hydroxylamine; In N,N-dimethyl-formamide;
DOI:10.2174/157340611796150923