{[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester

Base Information

• Chemical Name: {[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester
• CAS No.: 662165-89-1
• Molecular Formula: C₃₂H₄₄N₄O₁₁S
• Molecular Weight: 692.788
• Mol file: 662165-89-1.mol

Synonyms:{[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester

Chemical Property of {[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of {[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester

There total 1 articles about {[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

mafenide hydrochloride (138-37-4) + sodium 3,5-bis(bis((ethoxycarbonyl)methyl)aminomethyl)benzoate → {[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester (662165-89-1)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In chloroform; N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1039/b305179j

Reference yield: 93.0%

{[3-[(bis-ethoxycarbonylmethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester (662165-89-1) → {[3-[(bis-carboxymethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-carboxymethyl-amino}-acetic acid (662165-83-5)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; at 20 ℃; for 12h;

DOI:10.1039/b305179j

upstream raw materials:

mafenide hydrochloride

Downstream raw materials:

{[3-[(bis-carboxymethyl-amino)-methyl]-5-(4-sulfamoyl-benzylcarbamoyl)-benzyl]-carboxymethyl-amino}-acetic acid