4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide

Base Information

• Chemical Name: 4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide
• CAS No.: 83089-13-8
• Molecular Formula: C₁₁H₁₀N₂O₂S₂
• Molecular Weight: 266.345
• Mol file: 83089-13-8.mol

Synonyms:4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide

Chemical Property of 4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide

Chemical Property:

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Technology Process of 4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide

There total 1 articles about 4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

thiophene-2-carbaldehyde (98-03-3) + sulfanilamide (63-74-1) → 4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide (83089-13-8)

Guidance literature:

With acetic acid; In tetrahydrofuran; ethanol; at 75 ℃; for 6h;

DOI:10.14233/ajchem.2015.17627

Reference yield: 72.0%

4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide (83089-13-8) + water (7732-18-5) + copper dichloride → [Cu(4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide)2(H2O)2]Cl2*0.5H2O

Guidance literature:

4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide; water; copper dichloride; In methanol; dichloromethane; for 2h; Reflux;

With sodium hydroxide; In methanol; dichloromethane; pH=7 - 7.5; Reflux;

DOI:10.14233/ajchem.2015.17627

Reference yield: 66.0%

4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide (83089-13-8) + water (7732-18-5) + cobalt(II) chloride (7646-79-9,14543-09-0,16413-89-1) → [Co(4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide)2(H2O)2]Cl2*0.5H2O

Guidance literature:

4-[(thiophene-2-yl)methyleneamino]phenyl sulphonamide; water; cobalt(II) chloride; In methanol; dichloromethane; for 2h; Reflux;

With sodium hydroxide; In methanol; dichloromethane; pH=7 - 7.5; Reflux;

DOI:10.14233/ajchem.2015.17627

upstream raw materials:

thiophene-2-carbaldehyde

sulfanilamide