5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose

Base Information

• Chemical Name: 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose
• CAS No.: 217438-62-5
• Molecular Formula: C₂₄H₃₀ClNO₅Si
• Molecular Weight: 476.044

Synonyms:5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose

Chemical Property of 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose

There total 2 articles about 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E/Z)-5-O-(tert-Butyldiphenylsilyl)-3-deoxy-3-hydroxyimino-1,2-O-isopropylidene-α-D-erythro-pentofuranose (266306-54-1) → 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose (217438-62-5)

Guidance literature:

With tert-butylhypochlorite; In dichloromethane; at -10 ℃; for 0.25h;

Reference yield:

(3aR,5R,6aS)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one (75783-45-8) → 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose (217438-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₂OH*HCl, NaHCO₃ / aq. ethanol

2: t-BuOCl / CH₂Cl₂

With tert-butylhypochlorite; hydroxylamine hydrochloride; sodium hydrogencarbonate; In ethanol; dichloromethane;

DOI:10.1039/a806326e

Reference yield: 95.0%

cyclohexa-1,3-diene (1165952-91-9) + 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose (217438-62-5) → (3R,6R)-3-[5'-O-(tert-Butyldiphenylsilyl)-3'-deoxy-1',2'-O-isopropylidene-α-D-erythro-pentofuranos-3'-ylideneamino]-6-chlorocyclohexene N-oxide + (1S,4R)-3-aza-2-oxabicyclo<2,2,2>oct-5-ene hydrochloride (266306-44-9) + (3aR,5R,6aS)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one (75783-45-8)

Guidance literature:

With chloroform; In water; isopropyl alcohol; at 0 ℃; for 4h;

upstream raw materials:

(E/Z)-5-O-(tert-Butyldiphenylsilyl)-3-deoxy-3-hydroxyimino-1,2-O-isopropylidene-α-D-erythro-pentofuranose

(3aR,5R,6aS)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one

Downstream raw materials:

C₂₉H₃₆ClNO₅Si

(1S,4R)-3-aza-2-oxabicyclo<2,2,2>oct-5-ene hydrochloride

(3aR,5R,6aS)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-2H-furo[2,3-d][1,3]dioxol-6-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 217438-62-5 5-O-(tert-butyldiphenylsilyl)-3-chloro-3-deoxy-1,2-O-isopropylidene-3-C-nitroso-α-D-xylofuranose

Send

Send

Metric Ton KG G Pound L ML

Send

Send