1-(3-Bromopropyl)pyrrolidine hydrobromide

Base Information

• Chemical Name: 1-(3-Bromopropyl)pyrrolidine hydrobromide
• CAS No.: 88806-08-0
• Molecular Formula: C7H14 Br N . Br H
• Molecular Weight: 273.011
• Hs Code.: 2933990090
• European Community (EC) Number: 819-220-0
• DSSTox Substance ID: DTXSID80602864
• Mol file: 88806-08-0.mol

Synonyms:88806-08-0;1-(3-BROMOPROPYL)PYRROLIDINE HYDROBROMIDE;1-(3-BROMOPROPYL)-PYRROLIDINE HYDROBROMIDE;1-(3-bromopropyl)pyrrolidine;hydrobromide;1-(3-Bromopropyl)pyrrolidine HBr;MFCD07787235;1-(3-bromopropyl)-pyrrolidine, hydrobromide;SCHEMBL735632;DTXSID80602864;HKP0263;ZJKZPSKBJRBROE-UHFFFAOYSA-N;3-bromopropylpyrrolidine hydrobromide;AKOS015962526;1-(3-bromopropyl)pyrrolidinium bromide;CS-W007182;DS-6822;AC-17195;DA-31223;SY040487;C76980;1-(3-BROMOPROPYL)PYRROLIDINEHYDROBROMIDE;EN300-1081305;1-(3-Bromopropyl)pyrrolidine--hydrogen bromide (1/1)

Chemical Property of 1-(3-Bromopropyl)pyrrolidine hydrobromide

Chemical Property:

• Vapor Pressure: 0.0106mmHg at 25°C
• Boiling Point: 256.3°C at 760 mmHg
• Flash Point: 108.8°C
• PSA: 3.24000
• LogP: 2.76320
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 272.95508
• Heavy Atom Count: 10
• Complexity: 69.3

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(3-Bromopropyl)pyrrolidinehydrobromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)CCCBr.Br

Technology Process of 1-(3-Bromopropyl)pyrrolidine hydrobromide

There total 2 articles about 1-(3-Bromopropyl)pyrrolidine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-pyrrolidin-1-yl-propan-1-ol (19748-66-4) → 1-(3-bromopropyl)pyrrolidine hydrobromide (88806-08-0)

Guidance literature:

With hydrogen bromide; In toluene;

DOI:10.1071/CH07010

Reference yield:

→ 1-(3-bromopropyl)pyrrolidine hydrobromide (88806-08-0)

Guidance literature:

With hydrogen bromide; at 100 ℃;

Reference yield: 43.0%

C19H16FNO3 (1189572-67-5) + 1-(3-bromopropyl)pyrrolidine hydrobromide (88806-08-0) → C26H29FN2O3 (1189572-62-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 11h;

DOI:10.1016/j.bmcl.2009.07.023

upstream raw materials:

3-pyrrolidin-1-yl-propan-1-ol

Downstream raw materials:

N-(3-methyl-1,2,4-thiadiazol-5-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]-3-{[4-(3-pyrrolidin-1-ylpropoxy)phenyl]thio}pyridine-2-carboxamide

C₂₆H₂₉FN₂O₃

4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-(3-(pyrrolidin-1-yl)propyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile

Refernces

• 1、 Okimoto, Mitsuhiro,Yoshida, Takashi,Hoshi, Masayuki,Hattori, Kazuyuki,Komata, Masashi,Numata, Kaori,Tomozawa, Kenta. "Electrooxidative cyclization of hydroquinolyl alcohols, hydroquinolylamines, and dimethyl aminomalonates". . p. 236 - 242. Retrieved 2008/02/11.