N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Base Information

Chemical Name:N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide
CAS No.:1454906-84-3
Molecular Formula:C₂₂H₂₆Cl₂FN₃O₄S
Molecular Weight:518.437
Hs Code.:

Synonyms:N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Suppliers and Price of N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

There total 4 articles about N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1454906-83-2
N-((5-bromopyridin-2-yl)methyl)ethanesulfonamide

: 1454906-85-4
2,2-dichloro-1-((4S,5R)-4-(fluoromethyl)-2,2-dimethyl-5-(4-(trimethylstannyl)phenyl)oxazolidin-3-yl)ethanone

: 1454906-84-3
N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 18h; Inert atmosphere;

Reference yield:

: 173999-23-0
C-(5-bromo-pyridin-2-yl)-methylamine

: 1454906-84-3
N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1.5 h / 20 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane / 1-methyl-pyrrolidin-2-one / 18 h / 80 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; triethylamine; In 1-methyl-pyrrolidin-2-one; dichloromethane;

Reference yield:

: 97483-77-7
2-Cyano-5-bromopyridine

: 1454906-84-3
N-((5-(4-((4S,5R)-3-(2,2-dichloroacetyl)-4-(fluoromethyl)-2,2-dimethyloxazolidin-5-yl)phenyl)pyridin-2-yl)methyl)ethanesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tetrahydroborate; nickel(II) chloride hexahydrate / methanol / 14 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 4 h / 0 - 20 °C

3: triethylamine / dichloromethane / 1.5 h / 20 °C

4: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane / 1-methyl-pyrrolidin-2-one / 18 h / 80 °C / Inert atmosphere

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifuran-2-yl-phosphane; nickel(II) chloride hexahydrate; triethylamine; trifluoroacetic acid; In 1-methyl-pyrrolidin-2-one; methanol; dichloromethane;