(2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone

Base Information

• Chemical Name: (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone
• CAS No.: 22489-30-1
• Molecular Formula: C₁₄H₁₈O
• Molecular Weight: 202.296
• Mol file: 22489-30-1.mol

Synonyms:(2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone

Chemical Property of (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone

There total 61 articles about (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-(4-Methylphenyl)-4,5-dimethylcyclopent-2-enone (199799-26-3) → 2,3-dimethyl-3-(p-tolyl)cyclopentan-1-one (4608-44-0,22489-30-1,54750-41-3,111768-71-9,111768-72-0,145842-62-2,147129-24-6,147129-25-7,22489-37-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 8h; Ambient temperature;

DOI:10.1039/a706510h

Reference yield: 96.0%

4-methyl-4-p-tolyl-hex-5-enoic acid methyl ester (663919-53-7) → 2,3-dimethyl-3-(p-tolyl)cyclopentan-1-one (4608-44-0,22489-30-1,54750-41-3,111768-71-9,111768-72-0,145842-62-2,147129-24-6,147129-25-7,22489-37-8)

Guidance literature:

4-methyl-4-p-tolyl-hex-5-enoic acid methyl ester; With ammonia; lithium; In tetrahydrofuran;

With pyridinium chlorochromate on silica gel; In tetrahydrofuran; dichloromethane; Further stages.;

DOI:10.1016/j.tetlet.2003.10.164

Reference yield: 92.0%

(1S,2R,3S)-2,3-dimethyl-3-p-tolylcyclopentanol (145842-60-0) → (2R,3R)-2,3-dimethyl-3-p-tolylcyclopentanone (22489-30-1)

Guidance literature:

With tetrapropylammonium perruthennate; 4 A molecular sieve; 4-methylmorpholine N-oxide; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1039/c39920001695

upstream raw materials:

carbon monoxide

3-Methyl-3-(4-methylphenyl)-1,4-pentadien

2,3-dimethyl-3-(4-methylphenyl)-cyclopentanol

2-methyl-3-(4-methylphenyl)-2-cyclopentenone

Downstream raw materials:

α-cuparenone

2,3-dimethyl-3-(4-methylphenyl)-cyclopentanol

(+)-laurene

laurene