ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate

Base Information

• Chemical Name: ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate
• CAS No.: 1228305-28-9
• Molecular Formula: C₁₄H₁₇N₅O₂
• Molecular Weight: 287.321
• Mol file: 1228305-28-9.mol

Synonyms:ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate

Chemical Property of ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate

There total 1 articles about ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

3,5-diamino-1-phenyl-1,2,4-triazole (14575-59-8) + ethyl acetoacetate (141-97-9) → ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate (1228305-28-9) + C20H25N5O4 (1228305-27-8) + (E)-N-(5-amino-1-phenyl-1H-1,2,4-triazol-3-yl)-3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enamide

Guidance literature:

at 100 - 105 ℃; for 4h;

DOI:10.1016/j.tet.2010.03.009

Reference yield: 73.0%

ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate (1228305-28-9) → 3-amino-7-methyl-5-oxo-2-phenyl-5H-[1,2,4]triazolo[4,3-a]pyrimidin-2-ium-8-ide

Guidance literature:

With sodium; for 0.333333h; Reflux;

DOI:10.1016/j.tet.2010.03.009

Reference yield: 20.0%

ethyl 3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enoate (1228305-28-9) → 3,5-diamino-1-phenyl-1,2,4-triazole (14575-59-8) + (E)-N-(5-amino-1-phenyl-1H-1,2,4-triazol-3-yl)-3-(5-amino-1-phenyl-1H-1,2,4-triazol-3-ylamino)but-2-enamide

Guidance literature:

at 100 - 101 ℃; for 60h;

DOI:10.1016/j.tet.2010.03.009

upstream raw materials:

3,5-diamino-1-phenyl-1,2,4-triazole

ethyl acetoacetate

Downstream raw materials:

3,5-diamino-1-phenyl-1,2,4-triazole

C₂₀H₂₅N₅O₄